2025-26 Men’s Elite 8 Odds: Spreads, Lines, What to Know for all 4 Games

Some familiar names are making up this season’s Elite Eight.
Let’s check out the odds for the men’s Elite 8 at DraftKings Sportsbook as of March 28, as well as what to know about each game.
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SATURDAY, MARCH 28
Spread: Illinois -7.5
Moneyline: Illinois -305, Iowa +245
O/U: 137.5
What to know: For a second straight game, Iowa will take on a Big Ten foe, after the Hawkeyes upset 4-seed Nebraska in the Sweet 16. Upset has been the name of the game for Iowa so far, considering it defeated 1-seed and defending champion Florida in the Round of 32. Can the Hawkeyes make it three underdog wins in a row? The two teams faced off once in the regular season, with Illinois winning 75-69 on Iowa’s home floor. In terms of the Sweet 16, Illinois had what could be considered the more impressive win — a double-digit victory over 2-seed Houston.
No. 2 Purdue vs. No. 1 Arizona
Spread: Arizona -6.5
Moneyline: Arizona -270, Purdue +220
O/U: 153.5
What to know: This will be a battle of one team that was a national title favorite during the preseason (Purdue), and one that became a national title favorite as the season went along (Arizona). In truth, Purdue didn’t have a great regular season, suffering eight losses prior to the Big Ten Tournament. However, an impressive run to a Big Ten Tournament championship — including a win over Michigan in the title game — vaulted the Boilermakers to a 2-seed. Now, the Boilermakers get Arizona, which won the Big 12 Tournament title and put a hurtin’ on Arkansas in the Sweet 16. Will the Wildcats be too much for Purdue to handle?
SUNDAY, MARCH 29
No. 6 Tennessee vs. No. 1 Michigan
Spread: Michigan -7.5
Moneyline: Michigan -310, Tennessee +250
O/U: 146.5
What to know: The second-lowest seed to make it to the Elite Eight is Tennessee, after it upset 2-seed Iowa State in the Sweet 16, 76-62. Its reward? A date with Michigan, which has cruised in the Tournament so far, including a 90-77 win over Alabama in the Sweet 16. The Wolverines have covered their last two Tournament games, while Tennessee has covered all three of its postseason games, including as an underdog against ISU.
Spread: Duke -5.5
Moneyline: Duke -218, UConn +180
O/U: 134.5
What to know: For the second time this Tournament, the Blue Devils were forced to survive a scare, this time against 5-seed St. John’s. In the second half, Duke trailed 55-45, before outscoring the Red Storm 35-20 and escaping with an 80-75 win. Now, it will face a UConn program that has won two of the last three national titles, after the Huskies eked past Michigan State in the Sweet 16, in a game they led most of the way.
