2025-26 Men’s Final Four Odds: Spreads, Lines, What to Know About National Semis

The men’s Final Four is here.
Who is favored to make the national title game?
Let’s check out the odds at DraftKings Sportsbook as of March 29, as well as what to know about both games.
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SATURDAY, APRIL 4
No. 1 Michigan vs. No. 1 Arizona
Spread: Michigan -1.5
Moneyline: Michigan -118, Arizona -102
O/U: 157.5
What to know: Unsurprisingly, this one is essentially a pick ‘em, considering both teams have dominated their competition during the Tournament and over the course of the entire season. The Wolverines appear invincible heading into the Final Four, winning their four Tournament games by an average of 22.5 points, including a 33-point mauling of Tennessee in the Elite Eight. And offensively? Michigan is averaging 95.3 points per game. That’s a lot. As for Arizona, it has been no slouch during the Tournament either, winning its four postseason contests by 20.5 points per game, and scoring 89.5 points per game. In short, there will be no difference when it comes to recent form between these two teams. However, take this for what it’s worth: Michigan ended the regular season with an 8-point, Big Ten Championship Game loss to Purdue. The Wildcats beat Purdue by 15 in the Elite Eight. Something? Nothing? You be the judge.
No. 3 Illinois vs. No. 2 UConn
Spread: Illinois -2.5
Moneyline: Illinois -135, UConn +114
O/U: 139.5
What to know: Wow. Duke had UConn, until it didn’t. Now, the Huskies are one step closer to making their third title game in four years, should they get past the Illini. Illinois, somewhat surprisingly, opened as the favorite. UConn has arguably the best win of the Tournament to date, with that upset victory over Duke. The Huskies also know how to win tight ones, considering they beat Michigan State by four in the Sweet 16 and Duke by one in the Elite Eight. Will UConn’s momentum carry it past the Illini? The last time a team won three titles in four years was UCLA way back in the John Wooden days. History is inching closer.
